Document 0536
 DOCN  M9480536
 TI    Epidemic of herpes zoster following HIV epidemic in Manipur, India.
 DT    9410
 AU    Panda S; Sarkar S; Mandal BK; Singh TB; Singh KL; Mitra DK; Sarkar K;
       Tripathy SP; Deb BC; ICMR Unit for Research on AIDS in north eastern
       states of India,; Calcutta.
 SO    J Infect. 1994 Mar;28(2):167-73. Unique Identifier : AIDSLINE
       MED/94308574
 AB    Since 1989, injecting drug use (IDU) related HIV infection has affected
       thousands of young adults in Manipur, a north eastern state of India
       bordering Myanmar following a similar kind of epidemic in adjoining
       countries like Thailand and Myanmar. During a clinical surveillance of a
       group of HIV positive IDUs for a natural history study at Manipur,
       herpes zoster (HZ) emerged as the most specific early HIV related
       illness (positive predictive value of 100%) in patients belonging to the
       age group of 12-45 years. Data collected from the dermatology
       departments of the two main hospitals of the state revealed that there
       had been an epidemic of HZ since 1990 (rate of 1990 being 11.3/1000
       compared to 6.5/1000 in 1989, P value < 0.0001) among males of 12-45
       years. The epidemic of HZ has been attributed to the preceding epidemic
       of IDU related HIV in the same age and gender group occurring 1 year
       earlier. HZ should be recognised as a marker condition similar to
       tuberculosis indicating the necessity of screening for HIV in regions
       where the dual problem of IDU and HIV exist in young adults.
 DE    Adolescence  Adult  Age Factors  AIDS-Related Opportunistic
       Infections/*EPIDEMIOLOGY  Child  Comparative Study  *Disease Outbreaks
       Female  Herpes Zoster/*EPIDEMIOLOGY  Human  HIV Infections/*EPIDEMIOLOGY
       India/EPIDEMIOLOGY  Male  Middle Age  Predictive Value of Tests  Risk
       Factors  *Substance Abuse, Intravenous  JOURNAL ARTICLE

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